Winner-takes-all resource competition redirects cascading cell fate transitions
نویسندگان
چکیده
منابع مشابه
Winner takes all in a race for cell fate
The choice between alternative cell fates is fundamental to biology. The Gram-positive soil bacterium Bacillus subtilis can become competent for genetic transformation by external DNA or can form resistant spores. Although decades of work has elucidated much about the complex regulatory pathways that lead to these mutually exclusive fates (Dubnau and Losick, 2006), the decision mechanism that d...
متن کاملThe winner takes it all.
W e all make mistakes from time to time. I have made my fair share, but none of my mistakes have ever won a prize. In 2002 Lundbeck breached the UK industry code of practice in the way it advertised escitalopram (Cipralex). Escitalopram is the son of citalopram (Cipramil). The company claimed that its new drug, escitalopram was more effective than citalopram, even though the two drugs have exac...
متن کاملThe winner takes it all
We study competing first passage percolation on graphs generated by the configuration model. At time 0, vertex 1 and vertex 2 are infected with the type 1 and the type 2 infection, respectively, and an uninfected vertex then becomes type 1 (2) infected at rate λ1 (λ2) times the number of edges connecting it to a type 1 (2) infected neighbor. Our main result is that, if the degree distribution i...
متن کاملWinner-take-all price competition
This paper examines the competitiveness of winner-take-all price competition in homogeneous product oligopoly environments where underlying buyer demands and/or firms’ costs need not be continuous. Our analysis is motivated by the observation that a variety of economic settings have these features. For example, in 1996 an Ivy League university solicited bids from several vendors for its initiat...
متن کاملWinner-Takes-All based Multi-Strategy Learning for Information Extraction
The proliferation of information on the Internet has enabled one find any information he/she is looking for. Nevertheless, almost all of these informations are designed for human readers and are not machine readable. Information extraction is a task that addresses the above problem by extracting a piece of information from unstructured formats. This paper proposes a winner-takes-all based multi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2021
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21125-3